Lectures and Practicals (topics, presentations)

Time table of Lectures and Practicals General medicine - Teaching in English language

Immunology

General Microbiology (Microbiology I)

Special Microbiology (Microbiology II)

Immunology lectures

MONDAY 9:00 - 9:45

Educational Center Malá Hora 4B - Lecture hall, ground floor

Study year: 2024/2025, Summer Term, 2^nd year

Study program: General medicine in English language

Lecturer: doc. MUDr. E. Nováková, PhD.

doc. MUDr. V. Sadloňová, PhD.

MUDr. J. Kompaniková, PhD.

Week	Date	Topic
1	17.2.	Introduction to immunology.
2	24.2.	Cells and molecules of Immune system.
3	3.3	Innate and aquired immunity. Lymphatic tissues and organs.
4	10.3.	Nonspecific immunity – mechanism and functions.
5	17.3.	Antigens and receptors. Recognition of self and non-self.
6	24.3.	Specific immunity – molecules and immunoglobulins.
7	31.3.	Specific immunity - organs and cells.
8	7.4.	Lymphocytes – differentiation,activation, APC.
9	14.4.	Hypersensitivity. Possibilities of influencing immunity.
10	21.4.	Day off
11	28.4.	Autoimmunity.
12	5.5.	Transplant immunity.
13	12.5.	Tumor immunity.
14	19.5.	Immunotherapy.

Presentations - Immunology Lectures
*Introduction to immunology*
Nonspecific immunity – bariers, cells
Nonspecific immunity – mechanism and functions
Specific immunity – molecules, immunoglobulins
Specific immunity – organs and cells, differenciation
Bases of specificity
Lymphocytes – activation, APC
Regulation of immunity, cytokines
Hypersensitivity
Autoimmunity
Transplant immunity
Tumor immunity
Immunotherapy

Immunology practicals

Dpt. of Microbiology and Immunology

Malá Hora 4B – Education center, 3^rd floor - left

2^nd year, Summer term 2024/2025

Study program: General medicine in English language

Monday - Thursday

Groups and teachers according to schedule

Week	Date	Day	Topic
1.	17.2.-20.2.	Mon-Thu	Introduction. Safety in laboratory. Organization of study.
2.	24.2.-27.2.	Mon-Thu	Cells of immune system – blood count, blood smear.
3.	3.3.-6.3.	Mon-Thu	Nonspecific immunity – phagocytosis.
4.	10.3.-13.3.	Mon-Thu	Lysosyme, bactericidal activity of serum.
5.	17.3.-20.3.	Mon-Thu	Complement, CH50.
6.	24.3.-27.3.	Mon-Wed	Serological reactions - precipitation
7.	31.3.-3.4.	Mon-Thu	Serological reactions - agglutination
8.	7.4.-10.4.	Mon-Thu	TEST
9.	14.4.-17.4.	Mon-Thu	New methods in immunology - ELISA, WB.
10.	21.4. 22.4.-24.4.	Mon(Easter) Tue-Thu	Specific cell immunity - Tuberculin skin test. IGRA, ELISPOT.
11.	28.4.-30.5. 1.5.day off	Mon-Wed Thu	Imunology of vaccination Day off - substitution
12.	5.5.-7.5. 8.5.day off	Mon-Wed Thu	Autoantibodies. Immunofluorescence Day off - substitution
13.	12.5.-15.5.	Tue-Thu	Immunodefficiency.
14	19.5.-22.5.	Mon-Thu	Conclusions.Substitutions. Preterms.

Presentations - Immunology Practicals
Cells of immune system
Nonspecific immunity - phagocytosis
Lysosyme, complement, bactericidal activity of serum
Serological reactions
New methods - ELISA, WB
Skin test, IGRA
Immunodeficiences - laboratory diagnosis
Autoantibodies
Immunology of vaccination

Participation in practical exercises is mandatory.

Participation in practical exercises is possible only

at the time specified in the schedule according to

study groups, students are not allowed

to substitute for missed practical exercises

with another group.

In Martin 10.2.2025

doc. MUDr. E. Nováková, PhD.,

Head of Dpt. of Microbiology and Immunology

General Microbiology 1 - Lectures

MONDAY 7:30 - 9:00

Educational Center, Malá Hora 4B – Lecture hall, ground floor

2^nd year - summer semester of academic year 2024/2025

Study program: General Medicine in English Language

Lecturers: doc. MUDr. E. Nováková, PhD.

doc. MUDr. V. Sadloňová, PhD.

MUDr. J. Kompaniková, PhD.

Week	Date	Topic
1	17.2.	Structure of bacterial cell.
2	24.2.	Physiology and metabolism of bacterial cell.
3	3.3.	Genetics of bacterial cell.
4	10.3.	Pathogenicity of bacteria.
5	17.3.	Physiological microflora, biofilm.
6	24.3.	Pathogenesis of microbial infection.
7	31.3.	Antibiotics I.
8	7.4.	Antibiotics II.
9	14.4.	Disinfection. Sterilisation
10	21.4.	Day off
11	28.4.	Vaccines.
12	5.5.	Viruses - structure, therapy.
13	12.5.	Fungi- structure, therapy.
14	19.5.	Parasites - structure, therapy.

Presentations: General Microbiology - Lectures
Introduction to microbiology. Structure of bacterial cell
Physiology and metabolism of bacterial cell
Genetics of bacterial cell
Pathogenic potencial, physiological microflora
Pathogenesis of microbial infection
Antibiotics
Vaccines, desinfection

General Microbiology 1- Practicals

Dpt. of Microbiology and Immunology

Malá Hora 4B – Education center, 3rd floor left

Study year 2024/2025, Summer Term, 2^nd year

Study program: General Medicine in English Language

Monday - Thursday

Groups and teachers according to schedule

Week	Date	Topic
1	17.2.-20.2	Introduction. Safety in laboratory. Organization of study.
2	24.2.-27.2.	Microscopy, fixed smear, native smear.
3	3.3-6.3.	Gram staining.
4	10.3.-13.3.	Acid fast staining.
5	17.3.-20.3.	Burri India ink method.
6	24.3.-27.3.	Spores staining, metachromatic granules.
7	31.3.-3.4.	Cultivation I - types of cultivation media.
8	7.4.-10.4.	TEST
9	14.4.-17.4.	Cultivation II - growth of bacteria.
10	21.4. 22.4.-24.4.	Day off Biochemical properties of bacteria
11	28.4.-30.4. 1.5.	Identification of enzymes, toxins. Day off - substitution
12	5.5.-7.5. 8.5.	Anaerobic cultivation. Day off - substitution
13	12.5-15.5.	ATB susceptibility testing.
14	20.5.-23.5.	Conclusions.Substitution. CREDIT TEST.

Presentations: General Microbiology - Practicals
Microscopy, native smear, fixed smear.
Gram staining
Acid fast staining
Burri method
Spores staining. Metachromatic granules
Cultivation
Identification of biochemical properties and enzymes part I.
Identification of biochemical properties and enzymes part II.
Anaerobic bacteria
ATB susceptibility testing Participation in practical exercises is mandatory. Participation in practical exercises is possible only at the time specified in the schedule according to study groups, students are not allowed to substitute for missed practical exercises with another group. in Martin, 10.2.2025 doc.MUDr. E. Nováková, PhD. Head of dpt. of Microbiology and Immunology

Special Microbiology - Lectures

MICROBIOLOGY II - LECTURES

WEDNESDAY (week 1-14): 8,00 - 9,30

FRIDAY (week 7-13): 13,30-15,00

Winter Term 2024/2025, 3^rd year

Study program: General Medicine in English Language

Lecturer: doc. MUDr. E. Nováková, PhD.

doc. MUDr. V. Sadloňová, PhD.

MUDr. J. Kompaníková, PhD.

Week	Topic
1	Staphylococci. Other Gram positive cocci.
2	Streptococci. S. pneumoniae.
3	G- cocci. Neisseria sp., Haemophilus sp.
4	G – rods (Enterobacteriaceae - part I).
5	G – rods (Enterobacteriaceae - part II).
6	G – rods (Pseudomonas, others). G+ rods.
7	Anaerobic bacteria.
7 Friday	Day off. (Chlamydia. Spirochetes. Mycoplasma).
8	Viruses - introduction, structure, pathogenesis, immunity, therapy.
8 Friday	RNA viruses part I.
9	RNA viruses part II.
9 Friday	Hepatitis viruses, HIV, prions
10	DNA viruses.
10Friday	Parasitology.
11	Mycology.
11 Friday	Clinical microbiology - infections of RT, GIT.
12	Clinical microbiology - infections of UGT.
12 Friday	Clinical microbiology - infections of blood. Hemoculture.
13	Infections of CNS. Toxins.
13 Friday	Infections of fetus, newborns, elderly people.
14	Antibiotics.(Requested topic) Preterm. <output>Preterm - 15th of Dec. 2021, from 8,00 - 14,00</output> <output>Preterm - 15th of Dec. 2021, from 8,00 - 14,00</output>

Presentations: Special Microbiology - Lectures
Staphylococci and other Gram positive cocci
Streptococci. Streptococcus pneumoniae
G- cocci - Neisseria sp., Moraxella sp. Haemophilus sp.
G- rods - Enterobacteriaceae - Part I.
G- rods - Enterobacteriaceae - Part II.
G- rods - Pseudomonas, G+rods
Anaerobes
Mycoplasma, Spirochetes, Chlamydia, Rickettsia and related bacteria
Virology - introduction
RNA viruses
DNA viruses
RNA viruses, Hepatitis, HIV
Parasitology I
Parasitology II (toxoplasmosis, malaria)
Mycology
Infections of Respiratory tract, Gastrointestinal tract
Infections of Urogenital tract
Infections of blood, haemoculture
Infections of CNS. Toxins.
Infections of fetus, newborns, elderly people.
Antibiotics

It is not obligatory to be present in lectures, but it is sincerely recommended.

Recommended readings:

Murray: Medical microbiology., 8th edition
Microbiology and Immunology on line – English version
Dpt. of Microbiology and Immunology web
Barron: Medical Microbiology and Immunology – available on line

In Martin, 05. september 2024, doc. MUDr. Elena Nováková, PhD., Head of Dpt. of Microbiology and Immunology

Special Microbiology - Practicals

Information on possible changes in the organization

of teaching at Dpt. of Microbiology and Immunology

will be provided to students continuously

during the semester.

Participation in practical exercises is mandatory.

Participation in practical exercises is possible only

at the time specified in the schedule according to

study groups, students are not allowed

to substitute for missed practical exercises

with another group.

SPECIAL MICROBIOLOGY - PRACTICALS

Dpt. of Microbiology and Immunology,

Malá Hora 4B, 3^rd floor

(Mon - Thu, groups: acc. to schedule)

Winter Term 2024/2025, 3^rd year

Study Program: General Medicine in English Language

Lecturers:

doc. MUDr. Elena Nováková, PhD.

doc. MUDr. Vladimíra Sadloňová, PhD.

MUDr. Jana Kompaniková, PhD.

Week	Topic
1	Introduction.
2	Staphylococci.
3	Streptococci.
4	Neisseria. Haemophilus.
5	Corynebacterium sp., Bordetella.
6	G+rods. Pseudomonas.
7	Enterobacteriaceae.(day off THU31st october)
8	TEST. Anaerobic bacteria. Spirochetes.
9	Mycobacterium.
10	Virology.
11	Parasitology.
12	Mycology.
13	Conclusion.Consultations.
14	Substitution. Preterm.

Presentations: Special Microbiology - Practicals
Staphylococci
Streptococci
Neiseria, Haemophilus
Enterobacteriaceae
Bacillus. Pseudomonas, Listeria
Corynebacterium diphtheriae, Bordetella pertussis
Mycobacterium
Anaerobes, Treponema, Leptospira
Virology - diagnostic tests
Mycology
Parasitology

It is obligatory to be present at practicals. 1 abscence is tolerated.

Substitution of practicals is possible only in the week 14.

Recommended readings: Materials on web site of Dpt. of Microbiology and Immunology, handouts for practical.

In Martin, 5.9.2024

doc. MUDr. E. Nováková, PhD.,

Head of Dpt. of Microbiology and Immunology