Lectures and Practicals (topics, presentations)

Time table of Lectures and Practicals General medicine - Teaching in English language

Immunology

General Microbiology (Microbiology I)

Special Microbiology (Microbiology II)

Immunology lectures

TUESDAY 9,45-10,30

Educational center Malá Hora 4B - lecture hall, ground floor

Study year: 2022/2023, Summer Term, 2^nd year

Study program: General medicine in English language

Lecturer: MUDr. M. Neuschlová, PhD.

doc. MUDr. E. Nováková, PhD.

Week	Date	Topic
1	14.2.	Introduction to immunology. Cells and molecules of Immune system
2	21.2.	Innate and aquired immunity. Lymphatic tissues and organs
3	28.2.	Nonspecific immunity – mechanism and functions.
4	7.3.	Antisens and receptors. Recognition of self and non-self.
5	14.3.	Specific immunity – molecules and immunoglobulins.
6	21.3.	Specific immunity - organs and cells.
7	28.3.	Lymphocytes – differentiation,activation, APC.
8	4.4.	Regulation of immune response, cytokines.
9	11.4.	Day Off
10	18.4.	Hypersensitivity.
11	25.4.	Possibilities of influencing immunity.
12	2.5.	Autoimmunity.
13	9.5.	Transplant immunity. Tumor immunity.
14	16.5.	Immunotherapy.

Presentations - Immunology Lectures
*Introduction to immunology*
Nonspecific immunity – bariers, cells
Nonspecific immunity – mechanism and functions
Specific immunity – molecules, immunoglobulins
Specific immunity – organs and cells, differenciation
Bases of specificity
Lymphocytes – activation, APC
Regulation of immunity, cytokines
Hypersensitivity
Autoimmunity
Transplant immunity
Tumor immunity
Immunotherapy

Immunology practicals

Dpt. of Microbiology and Immunology, Malá Hora 4B – Edukačné centrum, 3^rd floor - left

Study year 2022/2023, summer term, 2^nd year

Study program: General medicine in English language

Groups and teachers acc. to schedule

Week	Date	Day	Topic
1.	13.2.-16.2.	Mon-Thu	Introduction. Safety in laboratory. Organization of study.
2.	20.2.-23.2.	Mon-Thu	Cells of immune system – blood count, blood smear.
3.	27.2.-2.3.	Mon-Thu	Nonspecific immunity – phagocytosis.
4.	6.3.-9.3.	Mon-Thu	Lysosyme, bactericidal activity of serum.
5.	13.3.-16.3.	Mon-Thu	Complement, CH50.
6.	20.3.-23.3.	Mon-Thu	Serological reactions - precipitation
7.	27.3.-30.3.	Mon-Thu	Serological reactions - agglutination
8.	3.4.-5.4. 6.4.	Mon-Wed Thu	New methods in immunology - ELISA, WB. Day off (groups 1,2,4) - substitution
9.	10.4.-13.4.	Mon-Thu	TEST
10.	17.4.-20.4.	Mon-Thu	Specific cell immunity - skin test, IGRA, ELISPOT.
11.	24.4.-27.4.	Mon-Thu	Imunology of vaccination-immune status tests.
12.	1.5. 2.5.-4.5.	Mon Tue -Thu	Day off (groups: 10, 11, 12 - substitution) Autoantibodies. Immunofluorescence.
13.	8.5. 9.5.-11.5.	Mon Tue-Thu	Day off (groups: 10, 11, 12 - substitution) Immunodefficiency.
14	15.5.-18.5.	Mon-Thu	Substitution. Preterms.

Presentations - Immunology Practicals
Cells of immune system
Nonspecific immunity - phagocytosis
Lysosyme, complement, bactericidal activity of serum
Serological reactions
New methods - ELISA, WB
Skin test, IGRA
Immunodeficiences - laboratory diagnosis
Autoantibodies
Immunology of vaccination

In Martin 07.2.2022

doc. MUDr. E. Nováková, PhD.,

Head of Dpt. of Microbiology and Immunology

General Microbiology - Lectures

Monday: 8,00-9,30

Educational center, Malá Hora 4B – Lecture hall, ground floor

2^nd year - summer semester of academic year 2022/2023

Study program: General Medicine in English Language

Lecturer: MUDr. J. Kompaniková, PhD.

MUDr. V. Sadloňová, PhD.

doc. MUDr. E. Nováková, PhD.

Week	Date	Topic
1	13.2.	Structure of bacterial cell.
2	20.2.	Physiology and metabolism of bacterial cell.
3	27.2.	Genetics of bacterial cell.
4	6.3.	Pathogenic potencial.
5	13.3.	Physiological microflora, biofilm.
6	20.3.	Pathogenesis of microbial infection.
7	27.3.	Antibiotics I.
8	3.4.	Antibiotics II.
9	10.4.	Day Off.
10	17.4.	Disinfection. Sterilisation
11	24.4.	Vaccines.
12	1.5.	Day off - Viruses - structure, therapy. (substitution)
13	8.5.	Day off - Fungi- structure, therapy. (substitution)
14	15.5.	Parasites - structure, therapy.

Presentations: General Microbiology - Lectures
Introduction to microbiology. Structure of bacterial cell
Physiology and metabolism of bacterial cell
Genetics of bacterial cell
Pathogenic potencial, physiological microflora
Pathogenesis of microbial infection
Antibiotics
Vaccines, desinfection

General Microbiology - Practicals

In person

Dpt. of Microbiology and Immunology

Malá Hora 4B – Edukačné centrum, 3rd floor left

Study year 2022/2023, Summer Term, 2^nd year

Study program: General Medicine in English Language

Groups and teachers acc. schedule

Week	Date	Day	Topic
1	13.2.-16.2	Mon-Thu	Introduction. Safety in laboratory. Organization of study.
2	20.2.-23.2.	Mon-Thu	Microscopy, fixed smear, native smear.
3	27.2.-2.3.	Mon-Thu	Gram staining.
4	6.3.-9.3.	Mon-Thu	Acid fast staining.
5	13.3.-16.3.	Mon-Thu	Burri India ink method.
6	20.3.-23.3.	Mon-Thu	Spores staining, metachromatic granules.
7	27.3.-30.3.	Mon-Thu	Cultivation I - types of cultivation media.
8	3.4.-5.4. 6.4.	Mon-Wed Thu	Cultivation II - growth of bacteria Day off (groups 1,2,4 - substitution)
9	10.4.-11.4. 12.4.-13.4.	Mon-Tue Wed - Thu	Day off TEST
10	17.4.-20.4.	Mon - Thu	Biochemical properties.
11	24.4.-27.4.	Mon-Thu	Identification of tools of pathogenicity - enzymes, toxins.
12	1.5. 2.5.-4.5.	Mon Tue-Thu	Day off - substitution Anaerobic cultivation.
13	8.5. 9.5.-11.5.	Mon Tue-Thu	Day off - substitution ATB susceptibility testing.
14	15.5.-18.5.	Mon-Thu	Substitution. CREDIT TEST.

Presentations: General Microbiology - Practicals
Microscopy, native smear, fixed smear.
Gram staining
Acid fast staining
Burri method
Spores staining. Metachromatic granules
Cultivation
Identification of biochemical properties and enzymes part I.
Identification of biochemical properties and enzymes part II.
Anaerobic bacteria
ATB susceptibility testing

Special Microbiology - Lectures

MICROBIOLOGY II - LECTURES

WEDNESDAY (week 1-14): 8,00 - 9,30

FRIDAY (week 7-13): 13,30-15,00

Winter Term 2023/2024, 3^rd year

Study program: General Medicine in English Language

Lecturer: doc. MUDr. E. Nováková, PhD.

MUDr. V. Sadloňová, PhD.

MUDr. M. Neuschlová, PhD.

MUDr. J. Kompaníková, PhD.

Week	Date	Topic
1	20.9.	Staphylococci. Other Gram positive cocci.
2	27.9.	Streptococci. S. pneumoniae.
3	4.10.	G- cocci. Neisseria sp., Haemophilus sp.
4	11.10.	G – rods (Enterobacteriaceae - part I).
5	18.10.	G – rods (Enterobacteriaceae - part II).
6	25.10.	G – rods (Pseudomonas, others). G+ rods.
7	1.11.	DAY OFF Anaerobic bacteria.
7 Friday	3.11.	Chlamydia. Spirochetes. Mycoplasma.
8	8.11.	Viruses - introduction, structure, pathogenesis, immunity, therapy.
8 Friday	10.11.	RNA viruses.
9	15.11.	DNA viruses.
9 Friday	17.11.	DAY OFF
10	22.11.	Hepatitis viruses, HIV, prions
10Friday	24.11.	Parasitology.
11	29.11.	Mycology.
11 Friday	1.12.	Clinical microbiology - infections of RT, GIT.
12	6.12.	Clinical microbiology - infections of UGT.
12 Friday	8.12.	Clinical microbiology - infections of blood. Hemoculture.
13	13.12.	Infections of CNS. Toxins.
13 Friday	15.12.	Infections of fetus, newborns, elderly people.
14	20.12	Antibiotics.(Requested topic) Preterm. <output>Preterm - 15th of Dec. 2021, from 8,00 - 14,00</output> <output>Preterm - 15th of Dec. 2021, from 8,00 - 14,00</output>

Presentations: Special Microbiology - Lectures
Staphylococci and other Gram positive cocci
Streptococci. Streptococcus pneumoniae
G- cocci - Neisseria sp., Moraxella sp. Haemophilus sp.
G- rods - Enterobacteriaceae - Part I.
G- rods - Enterobacteriaceae - Part II.
G- rods - Pseudomonas, G+rods
Anaerobes
Mycoplasma, Spirochetes, Chlamydia, Rickettsia and related bacteria
Virology - introduction
RNA viruses
DNA viruses
RNA viruses, Hepatitis, HIV
Parasitology I
Parasitology II (toxoplasmosis, malaria)
Mycology
Infections of Respiratory tract, Gastrointestinal tract
Infections of Urogenital tract
Infections of blood, haemoculture
Infections of CNS. Toxins.
Infections of fetus, newborns, elderly people.
Antibiotics

It is not obligatory to be present in lectures, but it is sincerely recommended.

Recommended readings:

Murray: Medical microbiology., 8th edition
Microbiology and Immunology on line – English version
Dpt. of Microbiology and Immunology web
Barron: Medical Microbiology and Immunology – available on line

In Martin, 05. september 2023, doc. MUDr. Elena Nováková, PhD., Head of Dpt. of Microbiology and Immunology

Special Microbiology - Practicals

Information on possible changes in the organization

of teaching at Dpt. of Microbiology and Immunology

will be provided to students continuously

during the semester.

Participation in practical exercises is mandatory.

Participation in practical exercises is possible only

at the time specified in the schedule according to

study groups, students are not allowed

to substitute for missed practical exercises

with another group.

SPECIAL MICROBIOLOGY - PRACTICALS

Dpt. of Microbiology and Immunology,

Malá Hora 4B, 3^rd floor

(Mon - Thu, groups: acc. to schedule)

Winter Term 2023/2024, 3^rd year

Study Program: General Medicine in English Language

Lecturers: doc. MUDr. Elena Nováková, PhD.

MUDr. Martina Neuschlová, PhD.

MUDr. Vladimíra Sadloňová, PhD.

MUDr. Jana Kompaniková, PhD.

Week	Date	Topic
1	18.9. - 21.9.	Introduction.
2	25.9. - 28.9.	Staphylococci.
3	2.10. - 5.10.	Streptococci.
4	9.10. - 12.10.	Neisseria. Haemophilus.
5	16.10. - 19.10.	Corynebacterium sp., Bordetella.
6	23.10. - 26.10.	G+rods. Pseudomonas.
7	30.10. - 2.11.	Enterobacteriaceae.
8	6.11. - 9.11.	Anaerobic bacteria. Spirochetes.
9.	13.11. - 16.11.	TEST Mycobacterium.
10	20.11. - 23.11.	Virology.
11	27.11. - 30.11.	Parasitology.
12	4.12. - 7.12.	Mycology.
13	11.12. - 14.12.	Conclusion.Consultations.
14	1.12. - 21.12.	Substitution. Preterm.

Presentations: Special Microbiology - Practicals
Staphylococci
Streptococci
Neiseria, Haemophilus
Enterobacteriaceae
Bacillus, Bordetella, Pseudomonas, Bacillus. Pseudomonas, Listeria
Corynebacterium diphtheriae. Mycobacterium I.
Mycobacterium II.
Anaerobes, Treponema, Leptospira
Virology
Mycology

It is obligatory to be present at practicals. 1 abscence is tolerated.

Substitution of practicals is possible only in the week 14.

Recommended readings: Materials on web site of Dpt. of Microbiology and Immunology, handouts for practical.

In Martin, 5.9.2022

doc. MUDr. E. Nováková, PhD.,

Head of Dpt. of Microbiology and Immunology