Student Scientific Activities

Clinical Immunology and Allergology

Title: Inflammatory Markers in the Diagnostics and Management of Autoinflammatory Diseases
Supervisor: MUDr. Anna Bobčáková, PhD.
Objective: Laboratory analysis, statistical evaluation, and comparison of inflammatory marker levels (IL-6, serum calprotectin, serum amyloid A, TNF-α, CRP, PCT, α1-acid glycoprotein) in a cohort of patients with autoinflammatory diseases in relation to disease activity.

Title: Application of Specific IgE Determination Using the Multiplex Method for the Selection of Allergen-Specific Immunotherapy
Supervisor: Ing. Jela Petrisková, PhD.
Objective: Utilization of multiplex determination of specific IgE against molecular allergen components in the diagnosis of allergic diseases and in the selection of appropriate allergen-specific immunotherapy.

Title: Activated T Lymphocytes in the Differential Diagnosis of Sepsis and Macrophage Activation Syndrome
Supervisor: RNDr. Martina Schniederová
Objective: Flow cytometric analysis of the profile of activated T lymphocytes (CD38^high / HLA-DR^+ CD8^+ T cells) in adult and pediatric patients with sepsis and hemophagocytic lymphohistiocytosis (HLH) for the purpose of differential diagnosis. The study will include statistical analysis and interpretation of the obtained results.

Transplantation Immunology

Title: Donor-Specific Antibodies and Kidney Transplant Rejection
Supervisor: Mgr. Andrej Čereš
Objective: Detection and monitoring of donor-specific antibodies (DSA) using the Luminex method, combined with a retrospective analysis of DSA in cases of graft injury, rejection, or dysfunction of the transplanted kidney.